Glaucocalyxin A

Research use only, not for human use.

Glaucocalyxin A-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery.

Glaucocalyxin A-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expression of X-linked inhibitor of apoptosis protein. Glaucocalyxin A inhibits Akt phosphorylation, suppresses proliferation, and promotes apoptosis in a dose-dependent manner, but not in normal glial cells. Glaucocalyxin A inhibits collagen-stimulated tyrosine phosphorylation of Syk, LAT, and phospholipase Cγ2, the signaling events in collagen receptor GPⅥ pathway. Glaucocalyxin A could potentially be developed as an antiplatelet and antithrombotic agent, can inhibit platelet p-selectin secretion and integrin activation by convulxin, is a GPVI selective ligand.

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Angiogenesis

EGFR

Caspase-3;Akt

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79498-31-0

332.44

C20H28O4

98%

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CC1(C2CC(C34C(C2(CCC1=O)C)CCC(C3O)C(=C)C4=O)O)C

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(-20℃)

With Ice Pack

≥ 2 years